Table 1 Sample demographics and clinical phenotype
From: Touch and olfaction/taste differentiate children carrying a 16p11.2 deletion from children with ASD
| N | ASD | 16p11.2 deletion | TD | Group differences |
|---|---|---|---|---|
| 121 | 17 | 45 | – | |
| Mean age (SD) | 5.49 (2.9) | 6.48 (1.5) | 5.85 (2.0) | ASD versus 16p11.2* |
| Gender (F/M) | 18/103 | 4/13 | 25/20 | ASD versus TD*** |
| 16p11.2 versus TD* | ||||
| ASD/non ASD | 121/0 | 10/7 | 0/45 | – |
| Full scale IQ (SD) | 79.4 (24.3) (n = 105) | 86.33 (11.6) (n = 15) | 115.70 (12.7) (n = 44) | ASD versus TD*** |
| 16p11.2 versus TD*** | ||||
| Verbal IQ (SD) | 80.1 (24.7) (n = 104) | 90.3 (10.8) (n = 15) | 116.6 (12.9) (n = 44) | ASD versus TD*** |
| 16p11.2 versus TD*** | ||||
| ASD versus 16p11.2** | ||||
| Nonverbal IQ (SD) | 86.7 (22.6) (n = 105) | 92.1 (12.1) (n = 17) | 112.6 (12.4) (n = 44) | ASD versus TD*** |
| 16p11.2 versus TD*** | ||||
| ADOS SA(SD) | 1.04 (0.3) (n = 112) | 0.68 (0.4) (n = 16) | – | ASD versus 16p11.2*** |
| ADOS RRB (SD) | 0.94 (0.4) (n = 111) | 0.71 (0.6) (n = 16) | – | |
| ADOS total (SD) | 1.01 (0.3) (n = 111) | 0.69 (0.4) (n = 16) | – | ASD versus 16p11.2*** |
| TDDT defensiveness (SD) | 0.29 (0.4) (n = 12) | 0.31 (0.4) (n = 16) | 0.06 (0.1) (n = 40) | ASD versus TD* |
| 16p11.2 versus TD** | ||||
| TDDT SSK (SD) | 0.16 (0.2) (n = 14) | 0.01 (0.0) (n = 16) | 0.00 (0.0) (n = 40) | ASD versus TD*** |
| ASD versus 16p11.2*** |